Dexmedetomidine or magnesium to control agitations in patients undergoing tonsillectomy: randomised controlled study

Saad, Beshoy Gamal Nazeem; Saad, Basem Boles Gabriale; Agamy, Ashraf EL Said Abd EL Rahman EL; Ammar, Mona Ahmed Abd Elmotalb; Khalaf, Khaled Moustafa Ali

doi:10.1186/s42077-023-00384-w

Dexmedetomidine or magnesium to control agitations in patients undergoing tonsillectomy: randomised controlled study

Authors

10.1186/s42077-023-00384-w

Abstract

Background
Preoperative time is a very stressful time for most patients undergoing surgery, particularly young patients. The primary goal of an anaesthesiologist is to reduce patients’ anxiety before surgery. To lessen this stress response, many anaesthetic pre-medications are used. Magnesium chloride and dexmedetomidine are two of these pre-medications that work well as sedatives. This study examined dexmedetomidine and magnesium sulphate as a pre-anaesthetic medication for kids. Dexmedetomidine and magnesium will be compared for their efficacy and safety in treating children who experience emerging anxiety after having their tonsils removed in this trial. Forty-five children between the ages of 4 and 12 years who were having elective adenotonsillectomy surgery in this comparative prospective, double-blind, randomised controlled clinical research. Children were split up into three groups: group A was given dexmedetomidine, group B was given magnesium infusion, and group C was given normal saline 0.9% infusion.
Results
Ramsay and Cravero scores revealed that children who got dexmedetomidine infusion were less agitated than those who received magnesium sulphate or normal saline infusion ( value 0.01).
Conclusions
When comparing dexmedetomidine to magnesium sulphate, there are a few advantages to its use. It can be administered as an anaesthetic medication to minors undergoing adenotonsillectomy under general anaesthesia in order to lessen postoperative agitation.

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