Comparison of the hypotensive efficacy of propofol infusion versus nitroglycerin infusion in functional endoscopic sinus surgery

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Abstract

Background
FESS is a common minimally invasive surgery that requires a clear field to be performed well. Hypotensive anesthesia is one of the most common maneuvers performed to help in keeping the field clear. An ideal drug for hypotensive anesthesia should be cheap and familiar to the anesthesiologist. So, being familiar with propofol and by using its cardio-depressant action, the idea of the research was developed. The idea of the study was to compare propofol infusion versus nitroglycerine infusion as a hypotensive agent.
Results
The mean duration of surgery was longer in the NTG to the propofol group. There was a high statistical significance in the average blood loss in the propofol group compared to the NTG group. The visibility of the operative field also was significant in the propofol group as compared with the NTG group. The mean heart rate in the NTG group was higher than the mean heart rate in the propofol group. The MAP in both groups was within a close range.
Conclusion
Propofol and NTG can produce a safe and effective controlled hypotension during FESS. Whereas, propofol has better surgical field visibility, less surgical bleeding, and less tachycardia during FESS.

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